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Sulfation of opioid drugs by human cytosolic sulfotransferases: Metabolic labeling study and enzymatic analysis

The current study was designed to examine the sulfation of eight opioid drugs, morphine, hydromorphone, oxymorphone, butorphanol, nalbuphine, levorphanol, nalorphine, and naltrexone, in HepG2 human hepatoma cells and human organ samples (lung, liver, kidney, and small intestine) and to identify the...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Sci
Main Authors: Kurogi, Katsuhisa, Chepak, Andriy, Hanrahan, Michael T., Liu, Ming-Yih, Sakakibara, Yoichi, Suiko, Masahito, Liu, Ming-Cheh
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459640/
https://ncbi.nlm.nih.gov/pubmed/24832963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2014.05.003
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