NKG2D is a Key Receptor for Recognition of Bladder Cancer Cells by IL-2-Activated NK Cells and BCG Promotes NK Cell Activation

Intravesical instillation of bacillus Calmette–Guérin (BCG) is used to treat superficial bladder cancer, either papillary tumors (after transurethral resection) or high-grade flat carcinomas (carcinoma in situ), reducing recurrence in about 70% of patients. Initially, BCG was proposed to work throug...

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Udgivet i:Front Immunol
Main Authors: García-Cuesta, Eva María, López-Cobo, Sheila, Álvarez-Maestro, Mario, Esteso, Gloria, Romera-Cárdenas, Gema, Rey, Mercedes, Cassady-Cain, Robin L., Linares, Ana, Valés-Gómez, Alejandro, Reyburn, Hugh Thomson, Martínez-Piñeiro, Luis, Valés-Gómez, Mar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459093/
https://ncbi.nlm.nih.gov/pubmed/26106390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00284
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