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Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone libraries

BACKGROUND: Clone libraries provide researchers with a powerful resource to study nucleic acid from diverse sources. Metagenomic clone libraries in particular have aided in studies of microbial biodiversity and function, and allowed the mining of novel enzymes. Libraries are often constructed by clo...

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Detaylı Bibliyografya
Yayımlandı:Microbiome
Asıl Yazarlar: Lam, Kathy N., Charles, Trevor C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459075/
https://ncbi.nlm.nih.gov/pubmed/26056565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-015-0086-5
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