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Andrographolide derivative AL-1 improves insulin resistance through down-regulation of NF-κB signalling pathway

BACKGROUND AND PURPOSE: Andrographolide is the most active constituent of the medicinal plant Andrographis paniculata. Previously, we synthesized a novel andrographolide derivative AL-1, conjugating andrographolide with lipoic acid. Although the antioxidative and/or anti-inflammatory activity of AL-...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Li, Yongmei, Yan, Hui, Zhang, Zaijun, Zhang, Gaoxiao, Sun, Yewei, Yu, Pei, Wang, Yuqiang, Xu, Lipeng
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459030/
https://ncbi.nlm.nih.gov/pubmed/25712508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13118
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