The GPR55 agonist lysophosphatidylinositol relaxes rat mesenteric resistance artery and induces Ca(2+) release in rat mesenteric artery endothelial cells

BACKGROUND AND PURPOSE: Lysophosphatidylinositol (LPI), a lipid signalling molecule, activates GPR55 and elevates intracellular Ca(2+). Here, we examine the actions of LPI in the rat resistance mesenteric artery and Ca(2+) responses in endothelial cells isolated from the artery. EXPERIMENTAL APPROAC...

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Vydáno v:Br J Pharmacol
Hlavní autoři: AlSuleimani, Y M, Hiley, C R
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459022/
https://ncbi.nlm.nih.gov/pubmed/25652040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13107
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