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Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding

The vimentin filament network plays a key role in cell architecture and signalling, as well as in epithelial–mesenchymal transition. Vimentin C328 is targeted by various oxidative modifications, but its role in vimentin organization is not known. Here we show that C328 is essential for vimentin netw...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Pérez-Sala, Dolores, Oeste, Clara L., Martínez, Alma E., Carrasco, M. Jesús, Garzón, Beatriz, Cañada, F. Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458873/
https://ncbi.nlm.nih.gov/pubmed/26031447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8287
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