Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

The intermediate filament protein vimentin constitutes a critical sensor for electrophilic and oxidative stress, which induce extensive reorganization of the vimentin cytoskeletal network. Here, we have investigated the mechanisms underlying these effects. In vitro, electrophilic lipids, including 1...

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Опубликовано в: :Redox Biol
Главные авторы: Mónico, Andreia, Duarte, Sofia, Pajares, María A., Pérez-Sala, Dolores
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Structure-function relationships of protein lipoxidation and mechanisms of action
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859561/
https://ncbi.nlm.nih.gov/pubmed/30658903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101098
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