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Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

The intermediate filament protein vimentin constitutes a critical sensor for electrophilic and oxidative stress, which induce extensive reorganization of the vimentin cytoskeletal network. Here, we have investigated the mechanisms underlying these effects. In vitro, electrophilic lipids, including 1...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Mónico, Andreia, Duarte, Sofia, Pajares, María A., Pérez-Sala, Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859561/
https://ncbi.nlm.nih.gov/pubmed/30658903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101098
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