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Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation

AIM: To investigate the continuous hepatic histopathological processes which occur in response to the loss of Dicer1. METHODS: We generated a hepatocyte-selective Dicer1 knockout mouse and observed the gradual hepatic histopathological changes in the mutant liver. Immunohistochemistry and Western bl...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Lu, Xu-Feng, Zhou, Yong-Jie, Zhang, Lei, Ji, Hong-Jie, Li, Li, Shi, Yu-Jun, Bu, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458769/
https://ncbi.nlm.nih.gov/pubmed/26074697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i21.6591
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