c-kit signaling differentially regulates ILC2 accumulation and susceptibility to CNS demyelination in male and female SJL mice

Multiple sclerosis (MS) preferentially affects women and this sex dimorphism is recapitulated in the SJL mouse model of MS, experimental autoimmune encephalomyelitis (EAE). Here we demonstrate that signaling through c-kit exerts distinct effects on EAE susceptibility in male and female SJL mice. Pre...

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Vydáno v:J Immunol
Hlavní autoři: Russi, Abigail E, Walker-Caulfield, Margaret E, Ebel, Mark E, Brown, Melissa A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458435/
https://ncbi.nlm.nih.gov/pubmed/25972476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500068
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