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Cancer Cell Surface Induced Peptide Folding Allows Intracellular Translocation of Drug
Many lead molecules identified in drug discovery campaigns are eliminated from consideration due to poor solubility and low cell permeability. These orphaned molecules could have clinical value if solubilized and delivered properly. SVS-1 is a de novo designed peptide that preferentially folds at th...
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| Publicado en: | J Control Release |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458427/ https://ncbi.nlm.nih.gov/pubmed/25979324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.05.267 |
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