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Transcription factors STAT6 and KLF4 implement macrophage polarization via the dual catalytic powers of MCPIP
Macrophage polarization plays a critical role in tissue homeostasis, disease pathogenesis, and inflammation and its resolution. IL-4-induced macrophage polarization involves induction of STAT6 and KLF4 that induce each other and promote M2 polarization. However, how these transcription factors imple...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458412/ https://ncbi.nlm.nih.gov/pubmed/25934862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402797 |
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