De novo Developed Antibodies to Donor Major Histocompatibility Complex Antigens Leads to Dysregulation of microRNAs and induction of MHC Class II

Immune responses to HLA and development of anti-donor HLA (DSA) have been shown to play a role in chronic rejection following transplantation. We hypothesized that Abs to MHC changes microRNAs (miRNAs) leading to chronic lung allograft rejection. Microarray analysis was performed in a murine model o...

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Publicado en:J Immunol
Main Authors: Xu, Zhongping, Nayak, Deepak K., Benshoff, Nicholas, Hachem, Ramsey, Gelman, Andrew E., Mohanakumar, Thalachallour
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458403/
https://ncbi.nlm.nih.gov/pubmed/25941328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401848
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