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Anthracycline Dose Intensification in Adult Acute Lymphoblastic Leukemia: Lack of Benefit in the Context of the Fractionated Cyclophosphamide, Vincristine, Doxorubicin, and Dexamethasone Regimen

BACKGROUND: In previous studies of frontline therapy for adult acute lymphoblastic leukemia (ALL), early treatment with higher doses of anthracyclines has been reported to improve outcome. The current study was conducted to evaluate whether addition of anthracycline-based consolidation chemotherapy...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Thomas, Deborah, O'Brien, Susan, Faderl, Stefan, Ravandi, Farhad, Jabbour, Elias, Pierce, Sherry, Cortes, Jorge, Kantarjian, Hagop
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458382/
https://ncbi.nlm.nih.gov/pubmed/20572037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25319
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