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Adults With Acute Lymphoblastic Leukemia and Translocation (1;19) Abnormality Have a Favorable Outcome With Hyperfractionated Cyclophosphamide, Vincristine, Doxorubicin, and Dexamethasone Alternating With Methotrexate and High-Dose Cytarabine Chemotherapy

BACKGROUND: Among the well described cytogenetic abnormalities in adults with acute lymphoblastic leukemia (ALL), a translocation involving chromosomes 1 and 19 (t[1;19] [q23;p13]) occurs in a small subset but has been associated variously with an intermediate prognosis or a bad prognosis in differe...

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Detalhes bibliográficos
Main Authors: Garg, Ravin, Kantarjian, Hagop, Thomas, Deborah, Faderl, Stefan, Ravandi, Farhad, Lovshe, Denise, Pierce, Sherry, O’Brien, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199455/
https://ncbi.nlm.nih.gov/pubmed/19298009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24266
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