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Robust and automated three-dimensional segmentation of densely packed cell nuclei in different biological specimens with Lines-of-Sight decomposition

BACKGROUND: Due to the large amount of data produced by advanced microscopy, automated image analysis is crucial in modern biology. Most applications require reliable cell nuclei segmentation. However, in many biological specimens cell nuclei are densely packed and appear to touch one another in the...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Autores principales: Mathew, B., Schmitz, A., Muñoz-Descalzo, S., Ansari, N., Pampaloni, F., Stelzer, E.H.K., Fischer, S.C.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458345/
https://ncbi.nlm.nih.gov/pubmed/26049713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0617-x
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