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Robust and automated three-dimensional segmentation of densely packed cell nuclei in different biological specimens with Lines-of-Sight decomposition

BACKGROUND: Due to the large amount of data produced by advanced microscopy, automated image analysis is crucial in modern biology. Most applications require reliable cell nuclei segmentation. However, in many biological specimens cell nuclei are densely packed and appear to touch one another in the...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Mathew, B., Schmitz, A., Muñoz-Descalzo, S., Ansari, N., Pampaloni, F., Stelzer, E.H.K., Fischer, S.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458345/
https://ncbi.nlm.nih.gov/pubmed/26049713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0617-x
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