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NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 Tat.

The Tat protein of human immunodeficiency virus type 1 enhances transcription by binding to a specific RNA element on nascent viral transcripts. Binding is mediated by a 10-amino acid basic domain that is rich in arginines and lysines. Here we report the three-dimensional peptide backbone structure...

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Bibliografiska uppgifter
Huvudupphovsmän: Mujeeb, A, Bishop, K, Peterlin, B M, Turck, C, Parslow, T G, James, T L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC44583/
https://ncbi.nlm.nih.gov/pubmed/8058789
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