NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 Tat.

The Tat protein of human immunodeficiency virus type 1 enhances transcription by binding to a specific RNA element on nascent viral transcripts. Binding is mediated by a 10-amino acid basic domain that is rich in arginines and lysines. Here we report the three-dimensional peptide backbone structure...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mujeeb, A, Bishop, K, Peterlin, B M, Turck, C, Parslow, T G, James, T L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44583/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8058789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.17.8248
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