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Calibrating ChIP-seq with nucleosomal internal standards to measure histone modification density genome-wide

Chromatin immunoprecipitation (ChIP) serves as a central experimental technique in epigenetics research, yet there are serious drawbacks: it is a relative measurement, which untethered to any external scale obscures fair comparison amongst experiments; it employs antibody reagents that have differin...

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Bibliografski detalji
Izdano u:Mol Cell
Glavni autori: Grzybowski, Adrian T., Chen, Zhonglei, Ruthenburg, Alexander J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458216/
https://ncbi.nlm.nih.gov/pubmed/26004229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.04.022
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