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Calibrating ChIP-seq with nucleosomal internal standards to measure histone modification density genome-wide
Chromatin immunoprecipitation (ChIP) serves as a central experimental technique in epigenetics research, yet there are serious drawbacks: it is a relative measurement, which untethered to any external scale obscures fair comparison amongst experiments; it employs antibody reagents that have differin...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458216/ https://ncbi.nlm.nih.gov/pubmed/26004229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.04.022 |
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