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Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice

Liver fibrosis is a pathological condition in which chronic inflammation and changes to the extracellular matrix lead to alterations in hepatic tissue architecture and functional degradation of the liver. Inhibitors of the enzyme soluble epoxide hydrolase (sEH) reduce fibrosis in the heart, pancreas...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Harris, Todd R., Bettaieb, Ahmed, Kodani, Sean, Dong, Hua, Myers, Richard, Chiamvimonvat, Nipavan, Haj, Fawaz G., Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458210/
https://ncbi.nlm.nih.gov/pubmed/25827057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.03.022
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