Cold denaturation of a repressor-operator complex: the role of entropy in protein-DNA recognition.
The mechanisms by which regulatory proteins recognize specific DNA sequences are not fully understood. Here we examine the basis for the stability of a protein-DNA complex, using hydrostatic pressure and low temperature. Pressure converts the DNA-binding Arc repressor protein from a native state to...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8058788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.17.8244 |
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