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Regulatory T cell identity: formation and maintenance
T regulatory (Treg) cells are central to the maintenance of immune homeostasis. The transcription factor Foxp3 is essential for specifying the Treg cell lineage during development, and continued expression of Foxp3 in mature Treg cells is necessary for suppressive function. Treg cells can lose Foxp3...
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| Pubblicato in: | Trends Immunol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458194/ https://ncbi.nlm.nih.gov/pubmed/25981968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.04.006 |
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