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Regulatory T cell identity: formation and maintenance
T regulatory (Treg) cells are central to the maintenance of immune homeostasis. The transcription factor Foxp3 is essential for specifying the Treg cell lineage during development, and continued expression of Foxp3 in mature Treg cells is necessary for suppressive function. Treg cells can lose Foxp3...
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| Publicado no: | Trends Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458194/ https://ncbi.nlm.nih.gov/pubmed/25981968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.04.006 |
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