ADF/cofilin-actin rods in neurodegenerative diseases

Dephosphorylation (activation) of cofilin, an actin binding protein, is stimulated by initiators of neuronal dysfunction and degeneration including oxidative stress, excitotoxic glutamate, ischemia, and soluble forms of β-amyloid peptide (Aβ). Hyperactive cofilin forms rod-shaped cofilin-saturated a...

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Publicado en:Curr Alzheimer Res
Main Authors: Bamburg, J.R., Bernstein, B.W., Davis, R.C., Flynn, K.C., Goldsbury, C., Jensen, J.R., Maloney, M.T., Marsden, I.T., Minamide, L.S., Pak, C.W., Shaw, A.E., Whiteman, I., Wiggan, O.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458070/
https://ncbi.nlm.nih.gov/pubmed/20088812
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