Improved Ancestry Estimation for both Genotyping and Sequencing Data using Projection Procrustes Analysis and Genotype Imputation

Accurate estimation of individual ancestry is important in genetic association studies, especially when a large number of samples are collected from multiple sources. However, existing approaches developed for genome-wide SNP data do not work well with modest amounts of genetic data, such as in targ...

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Udgivet i:Am J Hum Genet
Main Authors: Wang, Chaolong, Zhan, Xiaowei, Liang, Liming, Abecasis, Gonçalo R., Lin, Xihong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457959/
https://ncbi.nlm.nih.gov/pubmed/26027497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.04.018
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