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The DnaA Protein Is Not the Limiting Factor for Initiation of Replication in Escherichia coli

The bacterial replication cycle is driven by the DnaA protein which cycles between the active ATP-bound form and the inactive ADP-bound form. It has been suggested that DnaA also is the main controller of initiation frequency. Initiation is thought to occur when enough ATP-DnaA has accumulated. In t...

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Pubblicato in:PLoS Genet
Autori principali: Flåtten, Ingvild, Fossum-Raunehaug, Solveig, Taipale, Riikka, Martinsen, Silje, Skarstad, Kirsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457925/
https://ncbi.nlm.nih.gov/pubmed/26047361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005276
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