The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

Mitochondrial morphological and ultrastructural changes occur during apoptosis and autophagy, but whether they are relevant in vivo for tissue response to damage is unclear. Here we investigate the role of the optic atrophy 1 (OPA1)-dependent cristae remodeling pathway in vivo and provide evidence t...

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Gepubliceerd in:Cell Metab
Hoofdauteurs: Varanita, Tatiana, Soriano, Maria Eugenia, Romanello, Vanina, Zaglia, Tania, Quintana-Cabrera, Rubén, Semenzato, Martina, Menabò, Roberta, Costa, Veronica, Civiletto, Gabriele, Pesce, Paola, Viscomi, Carlo, Zeviani, Massimo, Di Lisa, Fabio, Mongillo, Marco, Sandri, Marco, Scorrano, Luca
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457892/
https://ncbi.nlm.nih.gov/pubmed/26039448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.05.007
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