The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

Mitochondrial morphological and ultrastructural changes occur during apoptosis and autophagy, but whether they are relevant in vivo for tissue response to damage is unclear. Here we investigate the role of the optic atrophy 1 (OPA1)-dependent cristae remodeling pathway in vivo and provide evidence t...

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Publicado en:Cell Metab
Autores principales: Varanita, Tatiana, Soriano, Maria Eugenia, Romanello, Vanina, Zaglia, Tania, Quintana-Cabrera, Rubén, Semenzato, Martina, Menabò, Roberta, Costa, Veronica, Civiletto, Gabriele, Pesce, Paola, Viscomi, Carlo, Zeviani, Massimo, Di Lisa, Fabio, Mongillo, Marco, Sandri, Marco, Scorrano, Luca
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457892/
https://ncbi.nlm.nih.gov/pubmed/26039448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.05.007
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