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Loss of Homogentisate 1,2-Dioxygenase Activity in Bacillus anthracis Results in Accumulation of Protective Pigment

Melanin production is important to the pathogenicity and survival of some bacterial pathogens. In Bacillus anthracis, loss of hmgA, encoding homogentisate 1,2-dioxygenase, results in accumulation of a melanin-like pigment called pyomelanin. Pyomelanin is produced in the mutant as a byproduct of disr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Han, Hesong, Iakovenko, Liudmyla, Wilson, Adam C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457819/
https://ncbi.nlm.nih.gov/pubmed/26047497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128967
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