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Loss of Homogentisate 1,2-Dioxygenase Activity in Bacillus anthracis Results in Accumulation of Protective Pigment

Melanin production is important to the pathogenicity and survival of some bacterial pathogens. In Bacillus anthracis, loss of hmgA, encoding homogentisate 1,2-dioxygenase, results in accumulation of a melanin-like pigment called pyomelanin. Pyomelanin is produced in the mutant as a byproduct of disr...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Han, Hesong, Iakovenko, Liudmyla, Wilson, Adam C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457819/
https://ncbi.nlm.nih.gov/pubmed/26047497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128967
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