DNA topology influences molecular machine lifetime in human serum

DNA nanotechnology holds the potential for enabling new tools for biomedical engineering, including diagnosis, prognosis, and therapeutics. However, applications for DNA devices are thought to be limited by rapid enzymatic degradation in serum and blood. Here, we demonstrate that a key aspect of DNA...

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Dettagli Bibliografici
Pubblicato in:Nanoscale
Autori principali: Goltry, Sara, Hallstrom, Natalya, Clark, Tyler, Kuang, Wan, Lee, Jeunghoon, Jorcyk, Cheryl, Knowlton, William B., Yurke, Bernard, Hughes, William L., Graugnard, Elton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2015
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457601/
https://ncbi.nlm.nih.gov/pubmed/25959862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr02283e
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