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DNA topology influences molecular machine lifetime in human serum

DNA nanotechnology holds the potential for enabling new tools for biomedical engineering, including diagnosis, prognosis, and therapeutics. However, applications for DNA devices are thought to be limited by rapid enzymatic degradation in serum and blood. Here, we demonstrate that a key aspect of DNA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nanoscale
Hauptverfasser: Goltry, Sara, Hallstrom, Natalya, Clark, Tyler, Kuang, Wan, Lee, Jeunghoon, Jorcyk, Cheryl, Knowlton, William B., Yurke, Bernard, Hughes, William L., Graugnard, Elton
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457601/
https://ncbi.nlm.nih.gov/pubmed/25959862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr02283e
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