DNA topology influences molecular machine lifetime in human serum

DNA nanotechnology holds the potential for enabling new tools for biomedical engineering, including diagnosis, prognosis, and therapeutics. However, applications for DNA devices are thought to be limited by rapid enzymatic degradation in serum and blood. Here, we demonstrate that a key aspect of DNA...

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Bibliographic Details
Published in:Nanoscale
Main Authors: Goltry, Sara, Hallstrom, Natalya, Clark, Tyler, Kuang, Wan, Lee, Jeunghoon, Jorcyk, Cheryl, Knowlton, William B., Yurke, Bernard, Hughes, William L., Graugnard, Elton
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2015
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457601/
https://ncbi.nlm.nih.gov/pubmed/25959862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr02283e
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