TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice

Neuropsychiatric disease is one of the most common manifestations of human systemic lupus erythematosus, but the mechanisms remain poorly understood. In human brain microvascular endothelial cells in vitro, TNF-like weak inducer of apoptosis (TWEAK) decreases tight junction ZO-1 expression and incre...

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Pubblicato in:J Autoimmun
Autori principali: Wen, Jing, Doerner, Jessica, Weidenheim, Karen, Xia, Yumin, Stock, Ariel, Michaelson, Jennifer S., Baruch, Kuti, Deczkowska, Aleksandra, Gulinello, Maria, Schwartz, Michal, Burkly, Linda C., Putterman, Chaim
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457585/
https://ncbi.nlm.nih.gov/pubmed/25911200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.03.005
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