TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice

Neuropsychiatric disease is one of the most common manifestations of human systemic lupus erythematosus, but the mechanisms remain poorly understood. In human brain microvascular endothelial cells in vitro, TNF-like weak inducer of apoptosis (TWEAK) decreases tight junction ZO-1 expression and incre...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Wen, Jing, Doerner, Jessica, Weidenheim, Karen, Xia, Yumin, Stock, Ariel, Michaelson, Jennifer S., Baruch, Kuti, Deczkowska, Aleksandra, Gulinello, Maria, Schwartz, Michal, Burkly, Linda C., Putterman, Chaim
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457585/
https://ncbi.nlm.nih.gov/pubmed/25911200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.03.005
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