BRCA Mutations Increase Fertility in Families at Hereditary Breast/Ovarian Cancer Risk

BACKGROUND: Deleterious mutations in the BRCA genes are responsible for a small, but significant, proportion of breast and ovarian cancers (5 - 10 %). Proof of de novo mutations in hereditary breast/ovarian cancer (HBOC) families is rare, in contrast to founder mutations, thousands of years old, tha...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Kwiatkowski, Fabrice, Arbre, Marie, Bidet, Yannick, Laquet, Claire, Uhrhammer, Nancy, Bignon, Yves-Jean
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457526/
https://ncbi.nlm.nih.gov/pubmed/26047126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127363
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