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BRCA Mutations Increase Fertility in Families at Hereditary Breast/Ovarian Cancer Risk
BACKGROUND: Deleterious mutations in the BRCA genes are responsible for a small, but significant, proportion of breast and ovarian cancers (5 - 10 %). Proof of de novo mutations in hereditary breast/ovarian cancer (HBOC) families is rare, in contrast to founder mutations, thousands of years old, tha...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457526/ https://ncbi.nlm.nih.gov/pubmed/26047126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127363 |
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