Synthetic Long Peptide Influenza Vaccine Containing Conserved T and B Cell Epitopes Reduces Viral Load in Lungs of Mice and Ferrets

Currently licensed influenza vaccines mainly induce antibodies against highly variable epitopes. Due to antigenic drift, protection is subtype or strain-specific and regular vaccine updates are required. In case of antigenic shifts, which have caused several pandemics in the past, completely new vac...

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Publicado en:PLoS One
Main Authors: Rosendahl Huber, S. K., Camps, M. G. M., Jacobi, R. H. J., Mouthaan, J., van Dijken, H., van Beek, J., Ossendorp, F., de Jonge, J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457525/
https://ncbi.nlm.nih.gov/pubmed/26046664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127969
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