Transmigration of Neutrophils across Inflamed Endothelium Is Signaled through LFA-1 and Src Family Kinase()

Leukocyte capture on inflamed endothelium is facilitated by a shift in LFA-1 from low to high affinity that supports binding to ICAM-1. LFA-1 bonds help anchor polymorphonuclear leukocytes (PMN) to inflamed endothelium in shear flow, and their redistribution to the leading edge guides pseudopod form...

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Vydáno v:J Immunol
Hlavní autoři: Sarantos, Melissa R., Zhang, Hong, Schaff, Ulrich Y., Dixit, Neha, Hayenga, Heather N., Lowell, Clifford A., Simon, Scott I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457456/
https://ncbi.nlm.nih.gov/pubmed/19050286
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