Transgenic Expression of Spi-C Impairs B Cell Development and Function by Affecting Genes Associated With BCR Signaling

Spi-C is an Ets family transcription factor closely related to PU.1 and Spi-B. Expression of Spi-C is developmentally regulated in the B cell lineage, but its function remains unknown. To determine the function of Spi-C in B cell development, we generated mice expressing a B cell-specific Spi-C tran...

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Vydáno v:Eur J Immunol
Hlavní autoři: Zhu, Xiang, Schweitzer, Brock L., Romer, Eric J., Sulentic, Courtney E. W., DeKoter, Rodney P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457361/
https://ncbi.nlm.nih.gov/pubmed/18792411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838323
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