The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats

Extracellular matrix (ECM) remodelling of the adipose tissue plays a pivotal role in the pathophysiology of obesity. The lysyl oxidase (LOX) family of amine oxidases, including LOX and LOX-like (LOXL) isoenzymes, controls ECM maturation, and upregulation of LOX activity is essential in fibrosis; how...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Dis Model Mech
Egile Nagusiak: Miana, María, Galán, María, Martínez-Martínez, Ernesto, Varona, Saray, Jurado-López, Raquel, Bausa-Miranda, Belén, Antequera, Alfonso, Luaces, María, Martínez-González, José, Rodríguez, Cristina, Cachofeiro, Victoria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457038/
https://ncbi.nlm.nih.gov/pubmed/26035864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020107
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