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Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila

Loss of mitochondrial function often leads to neurodegeneration and is thought to be one of the underlying causes of neurodegenerative diseases such as Parkinson's disease (PD). However, the precise events linking mitochondrial dysfunction to neuronal death remain elusive. PTEN-induced putative...

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Publicat a:Dis Model Mech
Autors principals: Sen, Aditya, Kalvakuri, Sreehari, Bodmer, Rolf, Cox, Rachel T.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457034/
https://ncbi.nlm.nih.gov/pubmed/26035866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019208
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