A carregar...
A functional link between the co-translational protein translocation pathway and the UPR
Upon endoplasmic reticulum (ER) stress, the transmembrane endoribonuclease Ire1α performs mRNA cleavage reactions to increase the ER folding capacity. It is unclear how the low abundant Ire1α efficiently finds and cleaves the majority of mRNAs at the ER membrane. Here, we reveal that Ire1α forms a c...
Na minha lista:
| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456659/ https://ncbi.nlm.nih.gov/pubmed/25993558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07426 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|