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Modulation of Human Valve Interstitial Cell Phenotype and Function Using a Fibroblast Growth Factor 2 Formulation

Valve interstitial cells (VICs) are fibroblastic in nature however in culture it is widely accepted that they differentiate into a myofibroblastic phenotype. This study assessed a fibroblast culture media formulation for its ability to maintain the phenotype and function of VICs as in the intact hea...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Latif, Najma, Quillon, Alfred, Sarathchandra, Padmini, McCormack, Ann, Lozanoski, Alec, Yacoub, Magdi H., Chester, Adrian H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456368/
https://ncbi.nlm.nih.gov/pubmed/26042674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127844
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