Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations

In sporadic colorectal cancer (CRC), the BRAF(V600E) mutation is associated with deficient mismatch repair (MMR) status and inversely associated with to KRAS mutations. In contrast to deficient MMR (dMMR) CRC, data on the presence of KRAS oncogenic mutations in proficient MMR (pMMR) CRC and their re...

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Bibliographic Details
Published in:PLoS One
Main Authors: Li, Wenbin, Zhi, Wenxue, Zou, Shuangmei, Qiu, Tian, Ling, Yun, Shan, Ling, Shi, Susheng, Ying, Jianming
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456280/
https://ncbi.nlm.nih.gov/pubmed/26042813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128202
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