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Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages

BACKGROUND: KRAS mutation occurs in 35%-40% of colorectal cancer (CRC). The aim of our study was to evaluate the pathological and molecular features of specific KRAS mutated colorectal carcinomas. KRAS and BRAF(V600E) mutation tests were performed in 762 primary tumors from a consecutive cohort stud...

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書誌詳細
出版年:BMC Cancer
主要な著者: Li, Wenbin, Qiu, Tian, Zhi, Wenxue, Shi, Susheng, Zou, Shuangmei, Ling, Yun, Shan, Ling, Ying, Jianming, Lu, Ning
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423107/
https://ncbi.nlm.nih.gov/pubmed/25929517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1345-3
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