snoRNA U17 Regulates Cellular Cholesterol Trafficking

Cholesterol is required for the growth and viability of mammalian cells, and is an obligate precursor for steroid hormone synthesis. Using a loss-of-function screen for mutants with defects in intracellular cholesterol trafficking, a Chinese hamster ovary cell mutant with haploinsufficiency of the U...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Jinn, Sarah, Brandis, Katrina A., Ren, Aileen, Chacko, Anita, Dudley-Rucker, Nicole, Gale, Sarah, Sidhu, Rohini, Fujiwara, Hideji, Jiang, Hui, Olsen, Brett N., Schaffer, Jean E., Ory, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456254/
https://ncbi.nlm.nih.gov/pubmed/25980348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.04.010
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