Switching from rivaroxaban to warfarin: an open label pharmacodynamic study in healthy subjects

AIMS: The primary objective was to explore the pharmacodynamic changes during transition from rivaroxaban to warfarin in healthy subjects. Safety, tolerability and pharmacokinetics were assessed as secondary objectives. METHODS: An open label, non-randomized, sequential two period study. In treatmen...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Moore, Kenneth Todd, Byra, William, Vaidyanathan, Seema, Natarajan, Jaya, Ariyawansa, Jay, Salih, Hiba, Turner, Kenneth C
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Clinical Trials
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456123/
https://ncbi.nlm.nih.gov/pubmed/25475601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12559
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