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The Na(+)/H(+) Exchanger-3 (NHE3) Activity Requires Ezrin Binding to Phosphoinositide and Its Phosphorylation

Na(+)/H(+) exchanger-3 (NHE3) plays an essential role in maintaining sodium and fluid homeostasis in the intestine and kidney epithelium. Thus, NHE3 is highly regulated and its function depends on binding to multiple regulatory proteins. Ezrin complexed with NHE3 affects its activity via not well-de...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Babich, Victor, Di Sole, Francesca
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455992/
https://ncbi.nlm.nih.gov/pubmed/26042733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129306
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