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Chronic regulation of the renal Na(+)/H(+) exchanger NHE3 by dopamine: translational and posttranslational mechanisms

The intrarenal autocrine/paracrine dopamine (DA) system contributes to natriuresis in response to both acute and chronic Na(+) loads. While the acute DA effect is well described, how DA induces natriuresis chronically is not known. We used an animal and a cell culture model to study the chronic effe...

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Autores principales: Hu, Ming Chang, Di Sole, Francesca, Zhang, Jianning, McLeroy, Paul, Moe, Orson W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651631/
https://ncbi.nlm.nih.gov/pubmed/23427139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00630.2012
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