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Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes.

Granzymes are a family of serine proteases that are harbored in cytoplasmic granules of activated T lymphocytes and are released upon target cell interaction. Immediate and complete neurite retraction was induced in a mouse neuronal cell line when total extracts of granule proteins were added. This...

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Bibliografiske detaljer
Main Authors: Suidan, H S, Bouvier, J, Schaerer, E, Stone, S R, Monard, D, Tschopp, J
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC44555/
https://ncbi.nlm.nih.gov/pubmed/8058766
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